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What Is Polynucleotides ?

Ameela is an innovative injectable solution based on natural polymerised polynucleotides. It’s a highly moisturizing gel that restores skin firmness and

is highly moisturizing, reduces wrinkles and fine lines and reduces dark circles and puffy eyes.


From £350 per session

Time of procedure

30 minutes​

Discomfort Level

1 out of 5​



Average Sessions Required

2-3 sessions

Natural Looking Results

Benefits of Polynucleotides

There are several benefits to Polynucleotides, which is why it’s such a popular option with many patients in our London practice. We’ve gone over just a few of the Polynucleotides benefits below.

Reduction of Fine Lines and Wrinkles

Polynucleotides treatment effectively targets fine lines and wrinkles, particularly in areas such as crow's feet, forehead lines, and smile lines. By stimulating collagen production, it helps plump and smooth the skin, leading to a noticeable reduction in the appearance of these signs of aging.

Enhanced Skin Elasticity

Over time, our skin tends to lose its elasticity, making it appear saggy and less youthful. Polynucleotides promote the production of elastin and collagen, which are essential proteins for maintaining skin's firmness and elasticity. This treatment helps the skin regain its suppleness, giving you a firmer, more youthful look.

Natural-Looking Results

Unlike some other facial aesthetic treatments that can lead to an unnatural or "frozen" appearance, Polynucleotides treatment provides results that look entirely natural. Your facial expressions remain intact, and the improvements are subtle yet highly effective, allowing you to maintain your unique and authentic appearance.

Minimal Downtime and Discomfort

Many patients appreciate the convenience of Polynucleotides treatment due to its minimal downtime. You can typically resume your daily activities immediately after the procedure. Discomfort is also kept to a minimum, thanks to the application of a topical numbing cream before treatment, ensuring your comfort throughout the process.

Why Have Polynucleotides At Twoth?

Choosing Twoth ensures unparalleled care and exceptional results. With a world-class team of professionals and personalized treatment, trust us for transformative dental and facial aesthetic treatments. A CQC registered clinic, Twoth combines expertise, advanced techniques, and a luxurious environment for the smile or rejuvenation you deserve.

Meet Your Doctor...

Dr Tara Francis
Aesthetics Director

Dr. Tara’s aim is to enhance the natural beauty we already possess. Tara prides herself on her ability to provide a welcoming, relaxed and caring environment for her patients. Tara’s passion in this industry is clear and ever growing, and this shows through her work, commitment to achieve excellence, and positive feedback from patients.

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From Dermal Fillers to Antiwrinkle treatments, we provide 0% payment plans to help separate the fees of your treatment.

Polynucleotides Treatment Journey

Your Polynucleotides treatment will be tailored to your exact requirements; therefore, one treatment can be very different from the next. However, we’ve provided a basic overview of a skin treatment below.

First step


During your consultation, our experienced medical team will assess your unique needs and goals. We'll discuss your medical history and expectations to create a personalised treatment plan.

second step


During your consultation, our experienced medical team will assess your unique needs and goals. We'll discuss your medical history and expectations to create a personalised treatment plan.

third step


Polynucleotides are carefully injected into the target areas using fine needles. The procedure is quick and relatively painless, and most patients experience minimal discomfort.

When you are done


After your treatment, it's crucial to follow these steps:

Avoid excessive sun exposure.
Use gentle skincare products and moisturize your skin regularly.

Fee Guide



Polynucleotide treatment Eyes or Face£350 per syringe
Price dependent on type used, and area treated. Price discussed during consultation.

Includes: Numbing Cream To Treatment Area, Consultation, Before & After Photos, After Care Pack

After Care of Polynucleotides

Avoid direct sun exposure

Avoid direct sunlight or tanning beds for at least one week.

Avoid excessive heat exposure

Apply a broad-spectrum sunscreen with an SPF of 30 or higher daily.

Use mild

Use mild, fragrance-free cleansers and moisturizers.

Avoid harsh chemical peels

Avoid harsh chemical peels or abrasive skincare products for the first week post-treatment.

Meet The Aesthetics Team


I have now visited Twoth on three different occasion... The first time was to take my son (8 years old) to see Dr Counihan for a braces consultation and my son absolutely loved the entire experience from start to finish. In fact, he was so excited and relaxed about it all he wanted to get started immediately.

The second time around, I went to see Dr Counihan myself for a second opinion and found the experience just as good as my son did

Karin Thyselius

Before I found Dr Neil Counihan I had a long history of dental trauma and sadly I repeatedly was subjected to very poor dentistry. I was scared to let anybody near my mouth and teeth. I had lost hope!

Dr Counihan made me the promise, with the right care I can keep my mouth healthy and definitely keep my teeth for the rest of my life.

And most importantly he made me feel safe and listened to

Neil M.

Frequently Asked Questions

Find the answer to the most common questions. Everything you need to know about Polynucleotides

Polynucleotides treatment is a non-surgical procedure that uses natural DNA components to rejuvenate the skin, reducing wrinkles and enhancing skin elasticity.

Polynucleotides stimulate collagen production, improving blood circulation to the treated area, resulting in reduced wrinkles and more youthful skin.

Most patients experience minimal discomfort during the procedure, and a topical numbing cream is applied for added comfort.

The treatment is quick, typically taking less than an hour to complete.

Mild swelling or redness at the injection site may occur but typically subsides within a few days.

Results can last up to several months or longer, depending on the individual’s skin and lifestyle factors.

There is minimal downtime, and most patients can return to their normal activities immediately.

Individuals looking to reduce wrinkles and improve skin elasticity without surgery are ideal candidates.

Polynucleotides are naturally occurring in our DNA, making the treatment safe and well-tolerated by most patients.

The number of treatments needed varies based on individual goals, but many patients see results with just one session. Your medical provider will advise you accordingly.

Patient care is our top priority